TikTok’s Beloved PDRN Emerges as the Latest Skincare Sensation

Polydeoxyribonucleotide (PDRN) is gaining widespread popularity as a skincare ingredient, particularly in Korean beauty treatments. Derived from salmon sperm cells, PDRN has been used in Korean clinical facial treatments for its anti-ageing benefits. The treatment, known as Rejuran Healer injections or the “salmon PDRN facial,” has garnered attention, especially after endorsements by celebrities like Kim Kardashian and Jennifer Aniston.

Alethea Demetriou from PureSeoul highlights that PDRN became well-known through social media platforms such as TikTok, where its ability to hydrate, improve skin elasticity, and boost collagen was promoted. This ingredient is becoming as popular as snail mucin, known for similar benefits, due to its gooey texture that intrigues consumers.

PDRN is noted for triggering the skin’s natural healing response, making it desirable for anti-ageing and skin-smoothing effects. Beauty experts, including Kristin Liang and Keon Kim, emphasize PDRN’s regenerative properties, citing its ability to accelerate wound healing, promote tissue regeneration, and address hyperpigmentation.

Additionally, PDRN’s composition is highly pure, free from impurities like proteins and lipids, which enhances its desirability in skincare formulations. With increasing competition among Korean clinics, the demand for affordable PDRN alternatives has risen, leading to the widespread availability of PDRN-based products like Medicube’s Pink Collagen Gel Mask across various retail channels.