Skincare Specialist Reveals ‘Powerful’ Ingredient ‘to Tackle Deep Wrinkles and Skin Sagging’

The skincare industry is embracing innovative treatments that combine polynucleotides and hyaluronic acid for enhanced skin health benefits. Hyaluronic acid is widely appreciated for its hydration capabilities, delivering immediate moisture to the skin. In contrast, polynucleotides, which are DNA fragments, stimulate the production of hyaluronic acid, regenerate fibroblast activity, and support collagen and elastin production. This results in improved structural integrity at a cellular level and promotes long-term skin renewal.

Polynucleotides are particularly effective for addressing deeper skin issues, such as deep wrinkles, sagging skin, atrophic scars, and inflammation-related skin conditions like eczema and rosacea. Unlike hyaluronic acid, which primarily hydrates, polynucleotides reduce inflammation and enhance healing, making them ideal for sensitive skin and post-procedure recovery, such as after laser treatments or chemical peels. They also contribute to blood vessel formation and help correct pigmentation issues such as melasma.

According to research published in the Journal of Cosmetic Dermatology, polynucleotide injections show promising results in improving skin texture and reducing wrinkles, which could be augmented by combining with other methods like microneedling for topical applications. Experts note that while hyaluronic acid remains excellent for hydration and fine line treatment, polynucleotides provide deeper, long-lasting regenerative benefits, making them suitable for aging or compromised skin.